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The Role of Pin1 in Controls Tumor Cell Proliferation in Mouse Lung Cancer Conditional Model

By Davide De Carlo

University of Milan, Italy

Cell Science

Published: Nov 30, 2017 | pg. no: 1-38

Abstract: There are some pathways that are altered in many tumors, and RB and p53 pathways are two of the most important. These proteins are regulated during carcinogenesis by a phosphorylation mechanism. Ser or Thr followed by Pro are major phosphorylation motifs in the cells but their significance was obscure until the discovery of the PIN1 protein (protein interacting with NIMA (never in mitosis A)-1) ...[Read more]

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Intralipid-A Magic Bullet?

By Joseph Eldor

Theoretical Medicine Institute, Israel

Vaccines

Published: Sep 15, 2017 | pg. no: 98

Abstract: Tubal disease is the cause of female infertility in approximately 30% of women and 10-25% of these are due to proximal tubal obstruction. Selective salpingography represent an approach in the diagnosis and treatment of proximal tubal abnormalities. Intralipid (IL) is a synthetic product composed of 10 % soybean oil, 1,2 % egg yolk phospholipids, 2.25 % glycerin, and water. When indicated, IL is in ...[Read more]

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The Sociologists’ Struggle for a European Identity

By Marinus Ossewaarde

University of Twente, Netherlands

Sociology

Published: Aug 10, 2017 | pg. no: 12

Abstract: In recent years, the European identity has been widely researched by sociologists who take an interest in mass and elite identification with the European project. In this article it is argued that the European identity is not only a research object for sociologists interested in identification: it is also their creation. Sociologists theorize and shape a European identity in, by and through their ...[Read more]

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Prevalence of Nasal Carriers of Methicillin Resistant Staphylococcus Aureus among Health Care Workers

By Shikhar Raj Thapa

Department of Medical Laboratory Technology, Tribhuvan University, India

Microbiology

Published: Jul 26, 2017 | pg. no: 1-25

Abstract: Background and objectives: Staphylococcal infections occur regularly in hospitalized patients and have severe consequences. Due to an increasing number of infections caused by Methicillin-Resistant Staphylococcus Aureus (MRSA) strains, which are now most often multiresistant, these strains impose an alarming threat to medical science. This study attempts to find out the prevalence of nasal carrier ...[Read more]

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Serendipity Based Medicine (SBM): To Infinity and Beyond

By Joseph Eldor

Theoretical Medicine Institute, Israel

Vaccines

Published: Jul 14, 2017 | pg. no: 48

Abstract: Serendipity means a "fortunate happenstance" or "pleasant surprise". Serendip is the Perso-Arabic name for Sri Lanka (Ceylon). How do we inspire new ideas that could lead to potential treatments for rare or neglected diseases, and allow for serendipity that could help to catalyze them? How we can build a more concrete structure for the "idea-hypothesis testing-proof of concept-translation-breakthr ...[Read more]

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