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Drug Discovery of Anticancer Agents from the Weeds of the Niligiris Using High Throughput Screening Techniques
By Chaitanya MVNL
Jagadguru Sri Shivarathreeshwara University, India
Complementary & Alternative Medicine
ISBN: 978-0-9967956-6-1
Published: Nov 16, 2016 | pg. no: 72
Abstract: Background: Weeds are store houses of complex bioactive secondary compounds which are the lead molecules for the discovery of pharmaceuticals like Adoniside from Adonis vernalis L., Asiaticoside from Centella asiatica , Silymarin from Silybum marianum (L.) Gaertn etc., which proved that weeds are the richest sources of new pharmaceuticals against many resistant diseases like cancer and tuberculosi ...[Read more]
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The Possible Cause of Polio, Post-Polio, CNS, PVIPD, Legionnaires, AIDS and the Cancer Epidemic - Mass Acidic Chemical Poisoning?
By Robert O Young
Universal Medical Imaging Group, USA
Published: Nov 14, 2016 | pg. no: 1-24
Abstract: There is now over 100 years of documented history and research on the Polio virus and whether or not its treatment by inoculation has been successful in eradicating Polio. I am suggesting in this article that there are significant findings based on historical and past and current research, including my own research that the theory of Polio and possibly other modern-day diseases, such as Post-Polio ...[Read more]
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In Silico Studies on HIV-1 Integrase Inhibitors: A Review
By Basheerulla Shaik
National Institute of Technical Teachers Training, India
Published: Oct 31, 2016 | pg. no: 1-31
Abstract: Acquired immunodeficiency syndrome (AIDS) is a formidable pandemic that is still creating havoc world-wide. The curative agent of this disease has been found to be a virus called human immunodeficiency virus of type-1 (HIV-1). In the replicative cycle of HIV-1, the integration of the viral DNA into host chromosomes is an essential step that is catalyzed by the enzyme integrase (IN). Inhibition of ...[Read more]
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MDM2-Mediated Degradation of SIRT6 Phosphorylated by AKT1 Promotes Tumorigenesis and Trastuzumab Resistance in Breast Cancer
By Umadevi Thirumurthi
The University of Texas, M.D. Anderson Cancer Center, USA
Published: Oct 28, 2016 | pg. no: 1-55
Abstract: Sirtuin6 (SIRT6) is one of the members of the Sirtuin family and functions as a longevity assurance gene by promoting genomic stability. It also regulates various cancer-associated pathways and was recently established as a bonafide tumor suppressor in colon cancer. This suggests that SIRT6 is an attractive target for pharmacological activation in cancer treatment, and hence, identification of pot ...[Read more]
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Influence of Seston Quality on Physiological Condition of Mytilus Edulis in Oligotrophic Lagoon
By Réjean Tremblay
Institut des Sciences de la Mer (ISMER), Canada
Published: Oct 22, 2016 | pg. no: 1-21
Abstract: Mytilus edulis culture depends on natural plankton with seasonal variations in dietary nutritional value. The microbial communities assimilated by M. edulis in Magdalen Islands lagoons (St. Lawrence Gulf, Canada), are mainly dominated by small heterotrophic eukaryotes, which vary taxonomically and in terms of lipid composition over the growing season. Particular lipids classes and fatty acids foun ...[Read more]
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